Sonidel SP100 Sonoporator - latest Ultrasound Technology from Sonidel Limited ®

SONIDEL SP100
[Sonoporator]

Are you interested in incorporating the latest Ultrasound technologies into your research methodologies for Gene Therapy and Drug Delivery Applications?

SONIDEL Limited specialises in the supply of sonoporation and electroporation equipment and accessories to the international medical research community. We have a particularly strong R&D interest in the provision of ultrasound solutions for Gene Therapy and Drug Delivery applications. To this end, we have developed various ultrasound (sonoporation) proprietary technologies and related patents and from this body of work have launched the World's First (low) cost-breakthrough high performance sonoporator, the SONIDEL SP100.

This device has been specifically designed for the medical research community as a low cost unit to facilitate the use and uptake of ultrasound as a viable research methodology. Using continuous and pulsed ultrasound it is possible to achieve transient membrane permeabilisation for applications such as:

Delivery of plasmids to cells and tissues for gene therapy-based applications and studies.
Delivery of nucleic acids such as siRNA, RNAi etc. to cells and tissues for studies on control of gene expression/gene therapy.
Delivery of cancer chemotherapeutic agents to impermeable target cells/tissues.
Delivery of agents to cells to study metabolic effects

Unlike other commercially produced sonoporation devices, the SONIDEL SP100:

is precision engineered to the highest standards
meets all relevant EU IEC standards for electrical and ultrasound safety
is a genuine low cost-breakthrough device
incorporates a consistent measurement capability that guarantees reproducible output from one device to the next and experimental results

As ultrasound does not travel very efficiently through air adequate contact with the ultrasound head is essential. Any compromise in this contact leads to a compromise in the dose of ultrasound delivered to the target. During treatment the SONIDEL SP100 constantly checks contact with the target. As soon as the acoustic contact is poor the operator is warned by means of an audio signal, the intensity will be reduced automatically and the treatment timer will stop. This ensures that the target receives the pre-determined dose of ultrasound and provides a warning to the operator if delivery of this dose is compromised by inadequate contact with the target.

The contact control in combination with an excellent beam characteristics, ensure that the SONIDEL SP100 is the highest quality ultrasound device currently on the market for the applications indicated above.
The contact control also prevents any undue heating resulting from a failed contact with the target and allows the operator to more reliably determine whether or not the target has been treated.

To complement the additional measurement control afforded by the SONIDEL SP100, we have also launched the World's First positive control kit for ultrasound-mediated transfection (SONIDEL STK10� Transfection Kit). All the components of the SONIDEL STK10 Transfection Kit� have been specifically calibrated and optimised for use with the SONIDEL SP100 sonoporator.

If you would like further information on how best to incorporate ultrasound solutions and methodologies into your particular research applications, please do not hesitate to contact us directly at:

Email: tech-support@sonidel.com

Download SONIDEL SP100 Brochure and In Vitro Application Results using the SP100 and STK10 Transfection Kit:
SONIDEL SP100 Specifications and Photographic Results

In Vivo Gene Expression Results using the SONIDEL SP100 Sonoporator and SONIDEL STK10 Transfection Kit